Cryoglobulinemia Vasculitis

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Cryoglobulinemia Vasculitis.

Cryoglobulinemic vasculitis (CryoVas) is a small-vessel vasculitis involving mainly the skin, the joints, the peripheral nervous system, and the kidneys. Type I CryoVas is single monoclonal immunoglobulins related to an underlying B-cell lymphoproliferative disorder. Type II and III cryoglobulins, often referred to as mixed cryoglobulinemia, consist of polyclonal immunoglobulin (Ig)G with or wi...

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The Spectrum of Type I Cryoglobulinemia Vasculitis

Type I cryoglobulinemia vasculitis (CryoVas) is considered a life-threatening condition; however, data on the characteristics and outcome are scarce. To analyze the presentation, prognosis, and efficacy and safety of treatments of type I CryoVas, we conducted a French nationwide survey that included 64 patients with type I CryoVas between January 1995 and July 2010: 28 patients with monoclonal ...

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Biopsy-Documented Myopathy and Vasculitis in Essential Mixed Cryoglobulinemia

A skeletal muscle involvement associated with skin, renal and liver pathology has been described in patients with essential mixed cryoglobulinemia. In some cases the muscle atrophy was consequence of a peripheral neuropathy but in such patients the muscle pathology has not been defined. Skin and skeletal muscle biopsies were performed in 6 patients with type II essential mixed cryoglobylinemia....

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Cryoglobulinemia vasculitis following intravesical instillations of bacillus Calmette-Guerin.

Infections and/or immune-mediated reactions may occur after intravesical instillation of bacillus Calmette-Guérin for the treatment of bladder carcinoma. We report herein a cryoglobulinemia vasculitis occurring after intravesical BCG instillation for a superficial papillary transitional cell bladder carcinoma. The patient, an 80-year-old man, presented peripheral ischemia 10 days after the seco...

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Leukocytoclastic Vasculitis in a Patient with Type 1 Cryoglobulinemia

Cutaneous manifestations of type 1 cryoglobulinemia are usually related to vascular occlusion by noninflammatory thrombosis; rarely is leukocytoclastic vasculitis seen in type 1 cryoglobulinemia. We report the case of a 64-year-old male who presented with isolated cutaneous leukocytoclastic vasculitis that was initially attributed to essential mixed cryoglobulinemia after thorough diagnostic ev...

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ژورنال

عنوان ژورنال: The American Journal of Medicine

سال: 2015

ISSN: 0002-9343

DOI: 10.1016/j.amjmed.2015.02.017